Bioscience

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Applied mathematician uses Maple to simulate the biomechanics of human bone microstructure Bone is a complex tissue, which is highly optimized for biological and mechanical functions. Researchers are currently examining how bone architecture changes with age and how it alters when various pathologies are present or absent. In particular, the prediction of bone fracture remains elusive.
All Ears  The ability to communicate is an elementary part of our lives. And without good hearing, communication becomes difficult if not impossible. This is why researchers continue to work on optimizing prostheses that improve hearing. Now researchers at the Universität Stuttgart in Germany have opened up a new avenue of exploration for developing middle ear prostheses. Their investigations concentrated on the impact of the ossicular chain in the middle ear, which directly affects hearing.
Maquet Critical Care: Breathe at ease Normally, when we want to breathe in, we just do it. But with artificial ventilation, how does the machine know how much air the patient needs, and when? Mechanical intervention can be stressful for the patient, and to minimize the discomfort, the machine must respond to the patient’s breath initiation as early as possible.

Protein Data Bank ( PDB ) Viewer There are many good molecule viewers; however, this viewer is different because it loads the entire molecule into a data structure ready to perform calculations with Maple. This is useful to test algorithms related to protein conformation and protein docking. It allows selecting a section of the molecule, and has an intuitive user-friendly graphical user interface. It requires as an input the section of a PDB files that contains the amino acid geometry (sample data is provided).